ICD-11 definition : Myasthenia gravis is the most common acquired auto-antibody mediated neuromuscular
transmission disorder. Prevalence is 1–2 per 10,000 persons. Fluctuating weakness
increasing with repeated activity and improving after a period of rest is the hallmark.
Myasthenia Gravis with antibodies directed against postsynaptic proteins, usually
the nicotinic acetylcholine receptor are the most prevalent. Other types are Myasthenia
Gravis associated with muscle-specific kinase antibodies and MG with unknown autoantibodies
(seronegative) Myasthenia Gravis. There are three groups: 1. Purely ocular Myasthenia
Gravis 2. Early-onset ( 40-50 years) generalized Myasthenia Gravis 3. Late-onset generalized
MG. In about 15%, the disease can be classified as paraneoplastic, usually associated
with a thymoma.;
Myasthenia gravis is the most common acquired auto-antibody mediated neuromuscular
transmission disorder. Prevalence is 1–2 per 10,000 persons. Fluctuating weakness
increasing with repeated activity and improving after a period of rest is the hallmark.
Myasthenia Gravis with antibodies directed against postsynaptic proteins, usually
the nicotinic acetylcholine receptor are the most prevalent. Other types are Myasthenia
Gravis associated with muscle-specific kinase antibodies and MG with unknown autoantibodies
(seronegative) Myasthenia Gravis. There are three groups: 1. Purely ocular Myasthenia
Gravis 2. Early-onset ( 40-50 years) generalized Myasthenia Gravis 3. Late-onset generalized
MG. In about 15%, the disease can be classified as paraneoplastic, usually associated
with a thymoma.