NCIt synonyms : Low Density Lipoprotein Receptor-Related Protein 6 Gene; FLJ90421; FLJ90062; ADCAD2; LDL Receptor Related Protein 6 wt Allele;
NCIt definition : Human LRP6 wild-type allele is located in the vicinity of 12p13.2 and is approximately
151 kb in length. This allele, which encodes low-density lipoprotein receptor-related
protein 6, is involved in the mediation of ligand endocytosis and cell communication.
Mutation of the gene is associated with autosomal dominant coronary artery disease
type 2.;