Nuclease-Sensitive Element-Binding Protein 1

Preferred Label : Nuclease-Sensitive Element-Binding Protein 1;

NCIt synonyms : CCAAT-Binding Transcription Factor I Subunit A; CBF-A; Y-Box-Binding Protein 1; EFI-A; Y-Box Transcription Factor; YB-1; DNA-Binding Protein B; Enhancer Factor I Subunit A; DBPB;

NCIt definition : Nuclease-sensitive element-binding protein 1 (324 aa, 36 kDa) is encoded by the human YBX1 gene. This protein plays a role in the mediation of mRNA splicing and transcriptional regulation.;

NCIt note : Nuclease-sensitive element-binding protein 1 binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. (UniProt);

Details

Origin ID

C93121;

UMLS CUI

C1312886;

Currated CISMeF NLP mapping
- Y-Box-Binding protein 1 [MeSH concept]
- y-box-binding protein 1 [MeSH Descriptor]
OMIM relation
- Y-box binding protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Y-Box-Binding protein 1 [MeSH concept]
- YBX1 protein, human [MeSH concept]
- YBX1 protein, human [MeSH Supplementary Concept]
- y-box-binding protein 1 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
- YBX1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- DBPB Transcriptional Activation Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Splicing [NCIt concept]
- Transcription [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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