Glasdegib - CISMeF

Preferred Label : Glasdegib;

NCIt definition : An orally bioavailable small-molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity. Glasdegib appears to inhibit Hh pathway signaling. The Hh signaling pathway plays an important role in cellular growth, differentiation and repair. Constitutive activation of Hh pathway signaling has been observed in various types of malignancies.;

UNII : K673DMO5H9;

InChIKey : SFNSLLSYNZWZQG-VQIMIIECSA-N;

CAS number : 1095173-27-5;

Molecule name : PF-04449913; PF 04449913;

NCI Metathesaurus CUI : CL412426;

Codes from synonyms : 246;

Details

Origin ID

C84862;

UMLS CUI

C4519273;

Automatic exact mappings (from CISMeF team)
- glasdegib [ATC Code]
Currated CISMeF NLP mapping
- Glasdegib [ICD-11 Extension code]
- Glasdegib (substance) [SNOMED CT concept]
- glasdegib [MeSH concept]
- glasdegib [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing glasdegib (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Glasdegib (substance) [SNOMED CT concept]
- Product containing glasdegib (medicinal product) [SNOMED CT concept]
- glasdegib [MeSH Supplementary Concept]
- glasdegib [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Glasdegib Maleate [NCIt concept]
has_target
- Protein Smoothened [NCIt concept]
is_free_acid_or_base_form_of
- Glasdegib Maleate [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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