Smoothened Receptor

Preferred Label : Smoothened Receptor;

MeSH definition : A frizzled-like, G-protein-coupled receptor that associates with PATCHED RECEPTORS to transduce signals from HEDGEHOG PROTEINS and initiate hedgehog signaling to ZINC FINGER PROTEIN GLI1. It may normally inhibit signaling in the absence of SONIC HEDGEHOG PROTEIN binding to PATCHED RECEPTOR-1.;

MeSH synonym : Receptor, Smoothened; Smoothened Protein; Smoothened Receptors; Receptors, Smoothened;

Wikipedia link : https://en.wikipedia.org/wiki/Smoothened receptor;

Details

Origin ID

D000072086;

UMLS CUI

C4277592;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Record concept(s)
- Smoothened Receptor [MeSH concept]
Related MeSH Supplementary Concept(s)
- SMO protein, human [MeSH Supplementary Concept]
- smo protein, Drosophila [MeSH Supplementary Concept]
- smo protein, mouse [MeSH Supplementary Concept]
- smo protein, rat [MeSH Supplementary Concept]
- smo protein, xenopus [MeSH Supplementary Concept]
- smo protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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