Tumor Suppressor ARF

Preferred Label : Tumor Suppressor ARF;

NCIt synonyms : p19(ARF); p14(ARF); ARF; CDKN2A-p14ARF; Alternative Reading Frame; Cyclin-Dependent Kinase Inhibitor 2A, Isoform 4;

NCIt definition : Tumor suppressor ARF (173 aa, 18 kDa) is encoded by the human CDKN2A gene. This protein is involved in cell cycle arrest.;

Details

Origin ID

C84349;

UMLS CUI

C2827404;

OMIM relation
- Cyclin-dependent kinase inhibitor 2a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CDKN2A Gene [NCIt concept]
- Cell Cycle Gene [NCIt concept]
- Cyclin-Dependent Kinase Inhibitor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Enzyme Inhibitor Protein [NCIt concept]
- Regulatory Protein [NCIt concept]
- Tumor Suppressor Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- CTCF Pathway [NCIt concept]
- Cyclin Regulation of Cell Cycle Pathway [NCIt concept]
- G2/M Checkpoint Pathway [NCIt concept]
- Ribosomal Biogenesis Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Melanoma [NCIt concept]
- Pancreatic Carcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Growth Regulation [NCIt concept]
- Negative Regulation of G2 Phase [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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