Preferred Label : Pixantrone Dimaleate;
NCIt synonyms : Pixantrone Maleate; 6,9-Bis((2-Aminoethyl)Amino)Benzo(g)Isoquinoline-5,10-Dione (2z)-But-2-Enedioate (1:2); Benz(g)Isoquinoline-5,10-Dione, 6,9-Bis((2-Aminoethyl)Amino)-, (2z)-2-Butenedioate
(1:2);
NCIt related terms : BBR 2778;
NCIt definition : The dimaleate salt of a synthetic, noncardiotoxic aza-anthracenedione analogue with
potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase
II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and
tumor cell cytotoxicity.;
Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It belongs
to the family of drugs called antitumor antibiotics.;
UNII : P0R64C4CR9;
InChIKey : SVAGFBGXEWPNJC-SPIKMXEPSA-N;
CAS number : 144675-97-8;
Drug name : Pixuvri;
Molecule name : BBR 2778; BBR-2778;
Chemical formula : C17H19N5O2.2C4H4O4;
NCI Metathesaurus CUI : CL408667;
Codes from synonyms : CDR0000322132;
Origin ID : C82398;
UMLS CUI : C2826149;
CISMeF manual mappings
Manual NTBT mappings (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to NTBT
concept_is_in_subset
has_free_acid_or_base_form
has_target
is_salt_form_of
http://www.has-sante.fr/portail/jcms/c_2725871/fr/pixuvri
http://www.has-sante.fr/portail/jcms/c_1626108/fr/pixuvri
http://www.has-sante.fr/portail/jcms/c_2725871/fr/pixuvri-pixantrone-anthracycline-et-apparente
2016
false
France
French
continuity of patient care
Pixantrone Dimaleate
guidelines for drug use
evaluation of the transparency committee
infusions, intravenous
pixantrone
pixantrone
pixantrone
lymphoma, Non-Hodgkin
adult
topoisomerase II inhibitors
topoisomerase II inhibitors
treatment outcome
survival analysis
isoquinolines
isoquinolines
B-cell non-Hodgkin lymphoma
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