" /> Dinaciclib - CISMeF





Preferred Label : Dinaciclib;

NCIt synonyms : 2-Piperidineethanol, 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5- a]pyrimidin-5-yl]-, (2S)-;

NCIt related terms : CDK inhibitor SCH 727965;

NCIt definition : A pyrazolo[1,5-a]pyrimidine with potential antineoplastic activity. Dinaciclib selectively inhibits cyclin dependent kinases CDK1, CDK2, CDK5, and CDK9; inhibition of CDK1 and CDK2 may result in cell cycle repression and tumor cell apoptosis.;

Alternative definition : NCI-GLOSS: A substance being studied in the treatment of advanced melanoma (a type of skin cancer) and other types of cancer. It blocks cell division and may cause cancer cells to die. It is a type of cyclin-dependent kinase inhibitor.;

UNII : 4V8ECV0NBQ;

InChIKey : PIMQWRZWLQKKBJ-SFHVURJKSA-N;

CAS number : 779353-01-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 779353-01-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : SCH 727965; MK-7965;

Chemical formula : C21H28N6O2;

Codes from synonyms : CDR0000662959; CDR0000662958; 160;

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07/05/2024


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