Transcriptional Repressor CTCF

Preferred Label : Transcriptional Repressor CTCF;

NCIt synonyms : 11-Zinc Finger Protein; CTCFL Paralog; 11 Zinc Finger Transcriptional Repressor; CCCTC-Binding Factor; CTCF;

NCIt definition : Transcriptional repressor CTCF (727 aa, 83 kDa) is encoded by the human CTCF gene. This soluble, nuclear protein may play a role in repressing cellular transcription in heterochromatin boundary regions.;

Details

Origin ID

C73704;

UMLS CUI

C1456335;

Currated CISMeF NLP mapping
- CCCTC-binding factor [MeSH concept]
OMIM relation
- Ccctc-binding factor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CTCF protein, human [MeSH concept]
- CTCF protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CTCF Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Chromatin Remodeling Factor [NCIt concept]
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
- Transcription Coactivator [NCIt concept]
- Transcription Repressor/Corepressor [NCIt concept]
gene_product_is_element_in_pathway
- CTCF Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Remodeling [NCIt concept]
- DNA Binding [NCIt concept]
- Epigenetic Process [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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