Eicosapentaenoic Acid

Preferred Label : Eicosapentaenoic Acid;

NCIt synonyms : All cis-5,8,11,14,17-Eicosapentaenoic Acid; Icosapentaenoic Acid; Timnodonic Acid; IPA;

NCIt related terms : Fatty Acid 20:5; EPA;

NCIt definition : An essential, polyunsaturated, 20-carbon omega-3 fatty acid with anti-inflammatory and potential antineoplastic and chemopreventive activities. Eicosapentaenoic acid (EPA) may activate caspase 3, resulting in apoptosis in susceptible tumor cell populations. In addition, this agent may inhibit cyclooxygenase-2 (COX-2), resulting in inhibition of prostaglandin synthesis and prostaglandin-mediated inflammatory processes.;

Alternative definition : CRCH: A class of polyunsaturated fatty acids with 20 carbons and 5 double bonds.;

CAS number : 25378-27-2;

Unit used : g;

Chemical formula : C20H30O2;

ChEBI ID : CHEBI:36006;

Details

Origin ID

C67080;

UMLS CUI

C0000545;

CISMeF manual mappings
- Eicosapentaenoic acid (substance) [SNOMED CT concept]
Currated CISMeF NLP mapping
- eicosapentaenoic acid [MeSH Descriptor]
- eicosapentaenoic acid [MeSH concept]
False automatic mappings
- Epichlorohydrin [LOINC component]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Eicosapentaenoic acid (substance) [SNOMED CT concept]
- Product containing eicosapentaenoic acid (medicinal product) [SNOMED CT concept]
- eicosapentaenoic acid [MeSH concept]
- eicosapentaenoic acid [MeSH Descriptor]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Caspase-3 [NCIt concept]
- Prostaglandin G/H Synthase 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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