Preferred Label : Daunorubicin;
NCIt synonyms : 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-,
(8S-cis)-; Leukaemomycin C; (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; Rubidomycin; Daunorrubicina; L-lyxo-Hexopyranoside, 3beta-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-metldioxo-1a-naphthacenyl
3-amino-2,3,6-trideoxy-,alpha-; DNR;
NCIt related terms : daunomycin; RUBOMYCIN C;
NCIt definition : An anthracycline antineoplastic antibiotic with therapeutic effects similar to those
of doxorubicin. Daunorubicin exhibits cytotoxic activity through topoisomerase-mediated
interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein
synthesis.;
Alternative definition : NCI-GLOSS: The active ingredient in a drug used to treat acute leukemias and some
other types of cancer. It blocks a certain enzyme needed for cell division and DNA
repair, and it may kill cancer cells. It is a type of anthracycline antibiotic and
a type of topoisomerase inhibitor.;
UNII : ZS7284E0ZP;
InChIKey : STQGQHZAVUOBTE-VGBVRHCVSA-N;
CAS number : 20830-81-3;
Chemical formula : C27H29NO10;
ChEBI ID : CHEBI:41977;
Codes from synonyms : CDR0000632148; NSC0082151; CDR0000045261; 143;
Origin ID : C62091;
UMLS CUI : C0011015;
False automatic mappings
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- has_salt_form
- has_target
- is_component_of_chemotherapy_regimen
- is_free_acid_or_base_form_of
