" /> Daunorubicin - CISMeF





Preferred Label : Daunorubicin;

NCIt synonyms : 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-; Leukaemomycin C; (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; Rubidomycin; Daunorrubicina; L-lyxo-Hexopyranoside, 3beta-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-metldioxo-1a-naphthacenyl 3-amino-2,3,6-trideoxy-,alpha-; DNR;

NCIt related terms : daunomycin; RUBOMYCIN C;

NCIt definition : An anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein synthesis.;

Alternative definition : NCI-GLOSS: The active ingredient in a drug used to treat acute leukemias and some other types of cancer. It blocks a certain enzyme needed for cell division and DNA repair, and it may kill cancer cells. It is a type of anthracycline antibiotic and a type of topoisomerase inhibitor.;

UNII : ZS7284E0ZP;

InChIKey : STQGQHZAVUOBTE-VGBVRHCVSA-N;

CAS number : 20830-81-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 20830-81-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C27H29NO10;

ChEBI ID : CHEBI:41977;

Codes from synonyms : CDR0000632148; NSC0082151; CDR0000045261; 143;

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14/05/2024


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