Preferred Label : Daunorubicin Hydrochloride;
NCIt synonyms : Daunorubicini Hydrochloridum; Cloridrato de Daunorubicina; Rubidomycin Hydrochloride; 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-,
(8S-cis)-, hydrochloride; 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-,
hydrochloride, (8S-cis)-(9CI); Daunoblastine; L-lyxo-Hexopyranoside, 3beta-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-metldioxo-1a-naphthacenyl
3-amino-2,3,6-trideoxy-,alpha-,hydrochloride; Daunomycin;
NCIt related terms : Daunomycin, hydrochloride; daunomycin hydrochloride; Daunorubicin.HCl; CERUBIDINE;
NCIt definition : The hydrochloride salt of an anthracycline antineoplastic antibiotic with therapeutic
effects similar to those of doxorubicin. Daunorubicin exhibits cytotoxic activity
through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication
and repair and RNA and protein synthesis.;
Alternative definition : NCI-GLOSS: A drug used to treat acute leukemias and some other types of cancer. It
blocks a certain enzyme needed for cell division and DNA repair, and it may kill cancer
cells. Cerubidine is a type of anthracycline antibiotic and a type of topoisomerase
inhibitor.;
UNII : UD984I04LZ;
InChIKey : GUGHGUXZJWAIAS-QQYBVWGSSA-N;
CAS number : 23541-50-6;
Drug name : Daunoblastin; Cerubidin; Ondena; Cerubidine; Daunoblastina; Rubilem;
Molecule name : FI-6339; RP-13057;
Chemical formula : C27H29NO10.HCl;
NSC code : 82151; 83142;
Codes from synonyms : NSC0082151; CDR0000632152; CDR0000583859; NSC0083142; 01604; CDR0000583858;
Origin ID : C1583;
UMLS CUI : C0282123;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- has_free_acid_or_base_form
- has_target
- is_component_of_chemotherapy_regimen
- is_salt_form_of
