Metoprolol - CISMeF

Preferred Label : Metoprolol;

NCIt definition : A cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction leading to a reduction in cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thereby preventing vasoconstriction and aldosterone secretion.;

UNII : GEB06NHM23;

InChIKey : IUBSYMUCCVWXPE-UHFFFAOYSA-N;

CAS number : 51384-51-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 51384-51-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C15H25NO3;

ChEBI ID : CHEBI:6904;

Codes from synonyms : 30286;

Details

Origin ID

C61845;

UMLS CUI

C0025859;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Metoprolol [ICD-11 Extension code]
- Metoprolol [LOINC component]
- Metoprolol (substance) [SNOMED CT concept]
- Product containing metoprolol (medicinal product) [SNOMED CT concept]
- metoprolol [ATC Code]
- metoprolol [Substance BNPC]
- metoprolol [MeSH concept]
- metoprolol [MeSH Descriptor]
- metoprolol [SNOMED Notion]
Validated automatic mappings to BTNT
- metoprolol [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Metoprolol Fumarate [NCIt concept]
- Metoprolol Succinate [NCIt concept]
- Metoprolol Tartrate [NCIt concept]
has_target
- Beta-1 Adrenergic Receptor [NCIt concept]
is_free_acid_or_base_form_of
- Metoprolol Fumarate [NCIt concept]
- Metoprolol Succinate [NCIt concept]
- Metoprolol Tartrate [NCIt concept]

Keyword's position in hierarchy(ies) :

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