Interleukin-23 Subunit Alpha

Preferred Label : Interleukin-23 Subunit Alpha;

NCIt synonyms : IL-23 p19; Interleukin 23; IL-23 Subunit Alpha; Interleukin 23, Alpha Subunit p19; SGRF Protein; Interleukin 23 Protein; Interleukin 23-Alpha; IL-23-A; Interleukin-23 Subunit p19; IL23A;

CISMeF acronym : IL-23A; IL23p19;

NCIt definition : Interleukin-23 subunit alpha (189 aa, 21 kDa) is encoded by the human IL23A gene. This protein plays a role in cytokine activity and immune response.;

NCIt note : Interleukin-23 is a heterodimer consisting of interleukin-12 subunit beta bound to interleukin-23 subunit alpha.;

Details

Origin ID

C61152;

UMLS CUI

C1700278;

Currated CISMeF NLP mapping
- IL23A protein, human [MeSH concept]
- IL23A protein, human [MeSH Supplementary Concept]
OMIM relation
- Interleukin 23-alpha [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- IL23A protein, human [MeSH concept]
- IL23A protein, human [MeSH Supplementary Concept]
Validated automatic mappings to NTBT
- Interleukin-23 [MeSH Descriptor]
- Interleukin-23 [MeSH concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- IL23A Gene [NCIt concept]
- Interleukin Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- ATF-2 Transcription Factor Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- IL23-Mediated Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
gene_product_is_physical_part_of
- Interleukin-23 [NCIt concept]
gene_product_plays_role_in_biological_process
- Antimicrobial Effect [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- NK Cell Activation [NCIt concept]
- T-Cell Receptor Activation [NCIt concept]
is_target
- Guselkumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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