NCIt definition : Human SP1 wild-type allele is located in the vicinity of 12q13.1 and is approximately
36 kb in length. This allele, which encodes transcription factor Sp1 protein, plays
a role in the regulation of transcription by RNA polymerase II.;
NCIt note : The SP1 gene product binds to GC box promoter elements and selectively activates mRNA
synthesis from genes that contain functional recognition sites (GeneCards).;