FLT3 wt Allele

Preferred Label : FLT3 wt Allele;

NCIt synonyms : CD135; FMS-Related Tyrosine Kinase 3 wt Allele; STK1; FLK2; FLT-3; FLK-2; RP11-153M24.3;

NCIt definition : Human FLT3 wild-type allele is located within 13q12 and is approximately 97 kb in length. This allele, which encodes receptor-type tyrosine-protein kinase FLT3 protein, is involved in hematopoiesis may function as a growth factor receptor on hematopoietic stem and/or progenitor cells.;

GenBank Accession Number : NM_004119;

Détails

Origin ID

C51546;

UMLS CUI

C1705127;

OMIM relation
- Fms-related tyrosine kinase 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 13: 27542750-27475753 [NCIt concept]
gene_in_chromosomal_location
- 13q12 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Acute Myeloid Leukemia with FLT3/ITD Mutation [NCIt concept]
- Myeloid/Lymphoid Neoplasms with FLT3 Rearrangement [NCIt concept]
gene_is_element_in_pathway
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Erythrocyte Differentiation Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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