Myeloid/Lymphoid Neoplasms with FLT3 Rearrangement

Preferred Label : Myeloid/Lymphoid Neoplasms with FLT3 Rearrangement;

NCIt synonyms : M/LN-eo with FLT3 Rearrangement; Myeloid/Lymphoid Neoplasm with FLT3 Rearrangement;

NCIt definition : Hematologic neoplasms characterized by the rearrangement of the FLT3 gene, most often resulting in the formation of t(12;13)(p13.2;q12.2)/ETV6-FLT3 fusion transcripts. Patients usually present with T-ALL or myeloid sarcoma.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1905748;

Details

Origin ID

C198559;

Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_excludes_molecular_abnormality
- BCR-ABL1 Fusion Protein Expression [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_molecular_abnormality
- FLT3 Gene Rearrangement [NCIt concept]
- Tyrosine Kinase Gene Fusion [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Pluripotent Stem Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
disease_mapped_to_gene
- FLT3 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- t(12;13)(p13.2;q12.2) [NCIt concept]
disease_may_have_molecular_abnormality
- ETV6-FLT3 Fusion Protein Expression [NCIt concept]
pathogenesis_of_disease_involves_gene
- FLT3 Gene [NCIt concept]
- FLT3 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients