NRG1 wt Allele

Preferred Label : NRG1 wt Allele;

NCIt synonyms : SMDF; Heregulin Gene; Neuregulin 1 wt Allele; ARIA; HRGA; NDF; GGF2; GGF; HGL; NEU Differentiation Factor Gene; HRG1; MSTP131; MST131; Heregulin, Alpha (45kD, ERBB2 p185-Activator) Gene; Heregulin, Alpha Gene; HRG; Acetylcholine Receptor Inducing Activity, Chick, Homolog of Gene;

NCIt definition : Human NRG1 wild-type allele is located within 8p21-p12 and is approximately 1,124 kb in length. This allele, which encodes pro-neuregulin-1, membrane-bound isoform protein, is involved in the compositional regulation of neurotransmitter receptors in maturing synapses in the brain, proliferation and differentiation.;

GenBank Accession Number : NM_013962;

Details

Origin ID

C51514;

UMLS CUI

C1705020;

Automatic exact mappings (from CISMeF team)
- ARIA [MedDRA LLT]
- ARIA-E [MedDRA LLT]
- Endothelial cell surface-expressed chemotaxis and apoptosis regulator [OMIM gene]
- Fibromatosis, gingival, 2 [OMIM Phenotype]
- Histidine-rich glycoprotein [OMIM gene]
- Neuregulin 1 [OMIM gene]
- Neuregulin-1 [MeSH Descriptor]
- Solute carrier family 48 (heme transporter), member 1 [OMIM gene]
- gingival fibromatosis, hereditary, 2 [ORDO Gene]
- histidine rich glycoprotein [ORDO Gene]
False automatic mappings
- fibromatosis, gingival, 2 [MeSH Supplementary Concept]
OMIM relation
- Neuregulin 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 8p21-p12 [NCIt concept]
gene_is_element_in_pathway
- Agrin Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- ERBB2/ERBB3 Signaling Pathway [NCIt concept]
- ERBB4 Signaling Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Family Pathway [NCIt concept]
- ErbB3 Receptor Recycling Pathway [NCIt concept]
- Glypican 1 Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Receptor Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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