Neuregulin-1 - CISMeF

Preferred Label : Neuregulin-1;

MeSH definition : A peptide factor originally identified by its ability to stimulate the phosphorylation the erbB-2 receptor (RECEPTOR, ERBB-2). It is a ligand for the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Variant forms of NEUREGULIN-1 occur through alternative splicing of its mRNA.;

MeSH synonym : nrg1 protein; ndf protein; neuregulin 1;

MeSH hyponym : glial growth factor; heregulin; neu differentiation factor; GGF Protein; Differentiation Factor, neu;

MeSH annotation : do not confuse X ref GLIAL GROWTH FACTOR with GLIA MATURATION FACTOR; do not confuse entry term GLIAL GROWTH FACTOR with GLIA MATURATION FACTOR;

Wikipedia link : https://en.wikipedia.org/wiki/Heregulin;

Is substance : O;

Details

Origin ID

D020890;

UMLS CUI

C0626201;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- NRG1 wt Allele [NCIt concept]
- Neuregulin [NCIt concept]
- Neuregulin 1 [OMIM gene]
- Recombinant Heregulin [NCIt concept]
- neuregulin 1 [HGNC gene]
Currated CISMeF NLP mapping
- Neuregulin-1 [NCIt concept]
Record concept(s)
- Neuregulin-1 [MeSH concept]
- glial growth factor [MeSH concept]
- heregulin [MeSH concept]
- neu differentiation factor [MeSH concept]
Related MeSH Supplementary Concept(s)
- NRG1 protein, gallus gallus [MeSH Supplementary Concept]
- NRG1 protein, human [MeSH Supplementary Concept]
- Nrg1 protein, mouse [MeSH Supplementary Concept]
- Nrg1 protein, rat [MeSH Supplementary Concept]
- Nrg1beta protein, mouse [MeSH Supplementary Concept]
- cimaglermin [MeSH Supplementary Concept]
- gamma-heregulin [MeSH Supplementary Concept]
- heregulin alpha [MeSH Supplementary Concept]
- heregulin beta (212-226) [MeSH Supplementary Concept]
- heregulin beta 1 (177-244) [MeSH Supplementary Concept]
- heregulin beta1 [MeSH Supplementary Concept]
- heregulin beta1-exotoxin [MeSH Supplementary Concept]
- neuregulin beta [MeSH Supplementary Concept]
- pro-neuregulin-alpha2C, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients