ADRA1B wt Allele

Preferred Label : ADRA1B wt Allele;

NCIt synonyms : ADRA1; Alpha-1B Adrenergic Receptor Gene; ALPHA1BAR; Adrenoceptor Alpha 1B wt Allele; Adrenergic, Alpha-1B-, Receptor Gene;

NCIt definition : Human ADRA1B wild-type allele is located within 5q23-q32 and is approximately 56 kb in length. This allele, which encodes alpha-1B adrenergic receptor protein, plays a role in the regulation of cellular growth and proliferation.;

NCIt note : ADRA1B is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.;

GenBank Accession Number : NM_000679;

Details

Origin ID

C51402;

UMLS CUI

C1706646;

Automatic exact mappings (from CISMeF team)
- Alpha-1b-adrenergic receptor [OMIM gene]
OMIM relation
- Alpha-1b-adrenergic receptor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 5: 159276318-159332129 [NCIt concept]
gene_in_chromosomal_location
- 5q23-q32 [NCIt concept]
gene_is_element_in_pathway
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
- Phospholipid Associated Cell Signaling Pathway [NCIt concept]
- Salivary Secretion Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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