IL3RA wt Allele

Preferred Label : IL3RA wt Allele;

NCIt synonyms : Interleukin 3 Receptor, Alpha (Low Affinity) wt Allele; CD123; IL3RAX; IL3RX; IL3R; IL3RY; hIL-3Ra; IL3RAY;

NCIt definition : Human IL3RA wild-type allele is located in the vicinity of either Xp22.3 or Yp22.33 and is approximately 46 kb in length. This allele, which encodes interleukin-3 receptor subunit alpha protein, is involved in the regulation of tyrosine phosphorylation activity, and promotes hematopoietic cell proliferation and differentiation.;

NCIt note : This gene is located in the pseudoautosomal region of chromosome Y;

GenBank Accession Number : NM_002183;

Details

Origin ID

C51365;

UMLS CUI

C1705980;

OMIM relation
- Interleukin 3 receptor, alpha [OMIM gene]
- Interleukin 3 receptor, y-chromosomal [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- X: 1499188-1545409 [NCIt concept]
gene_in_chromosomal_location
- Xp22.3 [NCIt concept]
- Yp11.3 [NCIt concept]
gene_is_element_in_pathway
- Apoptosis Pathway [NCIt concept]
- BAD Regulation Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- IL3 Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Immune Response Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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