IFNGR2 wt Allele

Preferred Label : IFNGR2 wt Allele;

NCIt synonyms : IFNGT1; Interferon Gamma Receptor 2 (Interferon Gamma Transducer 1) wt Allele; AF-1; IMD28; Interferon-Gamma Receptor, Accessory Factor For Gene; IFGR2;

NCIt definition : Human IFNGR2 wild-type allele is located in the vicinity of 21q22.11 and is approximately 35 kb in length. This allele, which encodes interferon gamma receptor 2 protein, plays a role in both innate immune responses to viral infection and host defense. The allele also is involved in the interferon gamma signal transduction pathway.;

GenBank Accession Number : NM_005534;

Details

Origin ID

C51355;

UMLS CUI

C1708410;

OMIM relation
- Interferon-gamma receptor 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Mycobacterial Infection [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 21: 33697072-33731696 [NCIt concept]
gene_in_chromosomal_location
- 21q22.11 [NCIt concept]
gene_is_element_in_pathway
- Chagas Disease Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- IFN Gamma Signaling Pathway [NCIt concept]
- Interferon Signaling Modulation Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
- T-Cell Polarization Pathway [NCIt concept]
- Th1/Th2 Differentiation Pathway [NCIt concept]
gene_plays_role_in_process
- Antiviral Response [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interferon Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients