NCIt synonyms : KUB2; X-ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break
Rejoining; Ku Autoantigen, 80kDa) Gene; Ku Antigen, 80-Kd Subunit Gene; G22P2; X-Ray Repair, Complementing Defective, In Chinese Hamster, 5 Gene; KARP1; KU80; NFIV; KARP-1; X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break
Rejoining) wt Allele; Ku86;
NCIt definition : Human XRCC5 wild-type allele is located within 2q35 and is approximately 99 kb in
length. This allele, which encodes X-ray repair cross-complementing protein 5, is
involved in double-strand break DNA repair and chromosomal translocation. A rare microsatellite
polymorphism in this allele is associated with cancer in patients of varying radiosensitivity.;