NCIt definition : Human IL13 wild-type allele is located in the vicinity of 5q31 and is approximately
3 kb in length. This allele, which encodes interleukin-13 protein, is involved in
both the regulation of immune responses and the modulation of B-cell maturation and
differentiation. The gene plays a role in the regulation of immunoglobulin E class
switching.;
NCIt note : Polymorphisms in the IL13 gene may be associated with increased risk for allergies
and asthma. The genes for IL3, IL5, IL4, IL13 and CSF2 form a cytokine gene cluster
on chromosome 5q.;