" /> Tandutinib - CISMeF





Preferred Label : Tandutinib;

NCIt synonyms : 1-Piperazinecarboxamide, 4-(6-Methoxy-7-(3-(1-piperidinyl)propoxy)-4-quinazolinyl)-N-(4-(1-methylethoxy)phenyl)-;

NCIt related terms : MLN518; CT53518;

NCIt definition : A piperazinyl quinazoline receptor tyrosine kinase inhibitor with antineoplastic activity. Tandutinib inhibits the autophosphorylation of FLT3 (FMS-Like Tyrosine kinase-3), c-KIT and PDGF (platelet-derived growth factor) receptor tyrosine kinases, thereby inhibiting cellular proliferation and inducing apoptosis.;

Alternative definition : NCI-GLOSS: A substance being studied in the treatment of some types of cancer. It may stop cancer cell growth by blocking certain enzymes. It may also prevent the growth of new blood vessels that tumors need to grow. It is a type of tyrosine kinase inhibitor and a type of antiangiogenesis agent.;

UNII : E1IO3ICJ9A;

InChIKey : UXXQOJXBIDBUAC-UHFFFAOYSA-N;

CAS number : 387867-13-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 387867-13-2 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : MLN 518; MLN518; CT53518;

Chemical formula : C31H42N6O4;

NSC code : 726292;

Codes from synonyms : CDR0000549426; CDR0000549427; CDR0000528028;

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14/05/2024


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