Upstream Stimulatory Factor 2

Preferred Label : Upstream Stimulatory Factor 2;

NCIt synonyms : FIP; USF2; FOS-Interacting Protein; Upstream Transcription Factor 2; Major Late Transcription Factor 2; bHLHb12; Class B Basic Helix-Loop-Helix Protein 12; c-Fos Interacting Protein;

NCIt definition : Upstream stimulatory factor 2 (346 aa, 37 kDa) is encoded by the human USF2 gene. This protein is involved in gene expression.;

NCIt note : Upstream stimulatory factor 2 is a bHLH transcription factor that binds to symmetrical E-box (5'-CACGTG-3') DNA sequences in viral and cellular promoters either as a homodimer or as a USF1/USF2 heterodimer (USF).;

Details

Origin ID

C38370;

UMLS CUI

C1447047;

OMIM relation
- Upstream transcription factor 2, fos-interacting [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- USF2 protein, human [MeSH concept]
- USF2 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
- USF2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- BHLH Protein [NCIt concept]
- Protein Complex Subunit [NCIt concept]
gene_product_has_structural_domain_or_motif
- bHLH Domain [NCIt concept]
gene_product_is_physical_part_of
- Upstream Stimulatory Factor [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients