" /> PR Domain Zinc Finger Protein 1 - CISMeF





Preferred Label : PR Domain Zinc Finger Protein 1;

NCIt synonyms : PR Domain Containing 1 with ZNF Domain Protein; PRDM1; PRDI-Binding Factor-1; Beta-Interferon Gene Positive-Regulatory Domain I Binding Factor; PRDI-BF1; B-Lymphocyte-Induced Maturation Protein 1; Positive Regulatory Domain I-Binding Factor 1; BLIMP1; PR Domain-Containing Protein 1; BLIMP-1; PR-Domain Zinc Finger Protein 1; PR-Domain Zinc Finger Protein-1; Beta-Interferon Gene Positive Regulatory Domain I-Binding Factor; PRDI-Binding Factor 1;

NCIt definition : PR domain zinc finger protein 1 (825 aa, 92 kDa) is encoded by the human PRDM1 gene. This protein is involved in the negative regulation of gene expression.;

NCIt note : PR-Domain Zinc Finger Protein 1 is a transcriptional repressor containing a SET domain and 4 C2H2-type zinc fingers. PRDM1 specifically binds to the PRDI (positive regulatory domain I) element of the beta-IFN gene promoter and represses beta-interferon gene expression. PRDM1 also drives maturation of B lymphocytes into Ig secreting cells. (SwissProt);

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13/05/2024


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