Origin Recognition Complex Subunit 1

Preferred Label : Origin Recognition Complex Subunit 1;

NCIt synonyms : HSORC1; ORC1; Replication Control Protein 1; ORC1L; Origin Recognition Complex Subunit 1-Like; PARC1; Origin Recognition Complex Subunit 1 Homolog-Like; Origin Recognition Complex 1; Origin Recognition Complex Subunit-1;

NCIt definition : Origin recognition complex subunit 1 (861 aa, 97 kDa) is encoded by the human ORC1 gene. This protein plays a role in DNA replication.;

NCIt note : Protein_Plays_Role_In_Biological_Process: Transcriptional Silencing;

Details

Origin ID

C34011;

UMLS CUI

C1335134;

Currated CISMeF NLP mapping
- origin recognition complex, subunit 1 [MeSH concept]
OMIM relation
- Origin recognition complex, subunit 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ORC1 protein, human [MeSH concept]
- ORC1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Cell Cycle Gene [NCIt concept]
- ORC1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_is_element_in_pathway
- CDK Regulation Pathway [NCIt concept]
- Cell Cycle Pathway [NCIt concept]
- E2F Transcription Factor Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Cell Viability Process [NCIt concept]
- DNA Binding [NCIt concept]
- Replication Initiation [NCIt concept]

Keyword's position in hierarchy(ies) :

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