General Transcription Factor 3C Polypeptide 3

Preferred Label : General Transcription Factor 3C Polypeptide 3;

NCIt synonyms : TFIIIC102; TFIIIC Gamma; Transcription Factor IIIC Subunit Gamma; TFIIIC 102 kDa Subunit; TF3C-Gamma; Transcription Factor IIIC 102kD; GTF3C3; Transcription Factor IIIC 102 kDa Subunit; General Transcription Factor IIIC3 102kDa; General Transcription Factor-IIIC3-102kDa;

NCIt definition : General transcription factor 3C polypeptide 3 (886 aa, 101 kDa) is encoded by the human GTF3C3 gene. This protein is involved in the transcription of genes with tRNA and virus-associated RNA promoters.;

NCIt note : General Transcription Factor IIIC3 102kDa is a subunit of GTF3C and contains N-terminal basic and acidic regions, a central acidic region, a C-terminal helix-loop-helix region, and 11 tetratricopeptide repeats. The GTF3C complex interacts with GTF3B in the recruitment of RNA polymerase III.;

Details

Origin ID

C29683;

UMLS CUI

C1333807;

OMIM relation
- General transcription factor 3c, polypeptide 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GTF3C3 protein, human [MeSH Supplementary Concept]
- GTF3C3 protein, human [MeSH concept]
gene_encodes_gene_product
- Basal Transcription Factor Gene [NCIt concept]
- GTF3C3 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Tetratricopeptide Repeat [NCIt concept]
gene_product_is_element_in_pathway
- RNA Polymerase III Transcription Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcription [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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