Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH Conjugate Vaccine

Preferred Label : Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH Conjugate Vaccine;

NCIt synonyms : Globo-H-GM2-Lewis-y-MUC1-32 aa sTn c TF c Tn c KLH Conjugate Vaccine;

NCIt definition : A heptavalent vaccine consisting of the tumor-associated carbohydrate antigens globohexaosylceramide (globo-H), GM2, Lewis-y, MUC1-32(aa), sTn(c), TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin (KLH), an immunomodulator. This vaccine may induce the production of IgG and IgM antibodies and an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens. (NCI04);

Details

Origin ID

C28551;

UMLS CUI

C1134578;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Ganglioside GM2 [NCIt concept]
- Globohexaosylceramide [NCIt concept]
- Lewis Y Antigen [NCIt concept]
- Mucin-1 [NCIt concept]
- Sialyl Tn Antigen [NCIt concept]
- Thomsen-Friedenreich Antigen [NCIt concept]
is_component_of_chemotherapy_regimen
- Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH Conjugate Vaccine/QS21 [NCIt concept]

Keyword's position in hierarchy(ies) :

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