Inhibin Beta A Chain

Preferred Label : Inhibin Beta A Chain;

NCIt synonyms : INHBA; Activin A; Activin AB Alpha; Inhibin Beta A; FSH-Releasing Protein; FSH-Releasing Factor; Erythroid Differentiation Protein; Inhibin, Beta-1; Inhibin Beta-A; Activin Beta-A Chain; Erythroid Differentiation Factor; Follicle-Stimulating Hormone-Releasing Protein;

NCIt definition : Inhibin beta A chain (426 aa, 47 kDa) is encoded by the human INHBA gene. This protein plays a role in the regulation of the secretion of follitropin by the pituitary gland.;

NCIt note : The inhibin beta A chain joins the inhibin alpha chain to form Inhibin-A, which inhibits follitropin production. Alternatively, the inhibin beta A chain protein is found in a homodimeric complex, called Activin A, or in a heterodimeric complex with the inhibin beta B chain, called Activin AB. The Activin complexes stimulate follitropin secretion. (UniProt);

Details

Origin ID

C28472;

UMLS CUI

C1570131;

Automatic exact mappings (from CISMeF team)
- Inhibin, beta a [OMIM gene]
- activin AB complex [GO term]
- activins [MeSH Descriptor]
- activins [MeSH concept]
- inhibin subunit beta A [ORDO Gene]
- inhibin-beta subunits [MeSH Descriptor]
- obsolete activin [GO term]
- transforming growth factor beta receptor binding [GO term]
Currated CISMeF NLP mapping
- Activin A (substance) [SNOMED CT concept]
- activin A [MeSH concept]
- activin A [MeSH Supplementary Concept]
- inhibin beta A subunit [MeSH Supplementary Concept]
- inhibin beta A subunit [MeSH concept]
OMIM relation
- Inhibin, beta a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- INHBA protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Growth Factor Gene [NCIt concept]
- INHBA Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
gene_product_is_physical_part_of
- Activin [NCIt concept]
- Inhibin A [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Regulation of Exocytosis [NCIt concept]
is_target
- Activin Type 2B Receptor Fc Fusion Protein STM 434 [NCIt concept]

Keyword's position in hierarchy(ies) :

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