Activin - CISMeF

Preferred Label : Activin;

NCIt definition : Disulfide-linked homo- and heterodimeric growth factors (Activin A, Activin B, Activin AB) of the TGF Family with effects on a range of cell types in addition to promoting FSH release in gonadal sites, depending on subunit composition. Composed of Beta-A and Beta-B subunits.;

NCIt note : Activin A is a homodimer of inhibin beta A chain. Activin B is a homodimer of inhibin beta B chain. Activin AB is a heterodimer of beta A and beta B.;

Details

Origin ID

C20456;

UMLS CUI

C0050668;

Automatic exact mappings (from CISMeF team)
- Inhibin, beta a [OMIM gene]
- transforming growth factor beta receptor binding [GO term]
Currated CISMeF NLP mapping
- Activin hormone (substance) [SNOMED CT concept]
- activin hormone [SNOMED Notion]
- activins [MeSH Descriptor]
- activins [MeSH concept]
False automatic mappings
- obsolete activin [GO term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
UMLS correspondences (same concept)
- Activin hormone (substance) [SNOMED CT concept]
- activin hormone [SNOMED Notion]
- activins [MeSH concept]
- activins [MeSH Descriptor]
Validated automatic mappings to BTNT
- Activin A (substance) [SNOMED CT concept]
- activin A [MeSH Supplementary Concept]
- activin A [MeSH concept]
gene_product_has_biochemical_function
- Growth Factor [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]
- Protein Secretion [NCIt concept]
has_gene_product_element
- Inhibin Beta A Chain [NCIt concept]
- Inhibin Beta B Chain [NCIt concept]
- Inhibin Beta E Chain [NCIt concept]

Keyword's position in hierarchy(ies) :

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