Inhibin Beta B Chain

Preferred Label : Inhibin Beta B Chain;

NCIt synonyms : INHBB; Inhibin Beta-2; Activin AB Beta; Beta-2 Inhibin; Inhibin Beta B; Activin Beta-B Chain; Activin AB Beta Polypeptide; Inhibin, Beta-2; Inhibin Beta-B;

NCIt definition : Inhibin beta B chain (407 aa, 45 kDa) is encoded by the human INHBB gene. This protein is involved in the modulation of follitropin secretion.;

NCIt note : The inhibin beta B chain joins the inhibin alpha chain to form Inhibin-B, which inhibits follitropin production. Alternatively, the inhibin beta B chain protein is found in a homodimeric complex, called Activin B, or in a heterodimeric complex with the inhibin beta A chain, called Activin AB. The Activin complexes stimulate follitropin secretion. (UniProt);

Details

Origin ID

C28473;

UMLS CUI

C1447906;

Automatic exact mappings (from CISMeF team)
- Inhibin, beta b [OMIM gene]
- activin AB complex [GO term]
- beta-inhibin (67-94) [MeSH Supplementary Concept]
- beta-inhibin (67-94) [MeSH concept]
OMIM relation
- Inhibin, beta b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- INHBB protein, human [MeSH Supplementary Concept]
- INHBB protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Growth Factor Gene [NCIt concept]
- INHBB Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
gene_product_is_physical_part_of
- Activin [NCIt concept]
- Inhibin B [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Regulation of Exocytosis [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients