Multi-neo-epitope Vaccine OSE 2101

Preferred Label : Multi-neo-epitope Vaccine OSE 2101;

NCIt synonyms : Tedopi;

NCIt related terms : EP-2101;

NCIt definition : A proprietary cancer DNA vaccine that contains multiple natural and modified epitopes derived from the four tumor associated antigens, CEA, HER2/neu, p53, and MAGE 2/3. EP-2101 also includes CAP1-6D, a heteroclitic CEA analog, and PADRE, a proprietary universal T-cell epitope that serves to enhance the immunogenicity of the epitopes. This agent has been shown to elicit cytotoxic T-lymphocyte responses against tumor cells expressing these multiple epitopes. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called cancer vaccines.;

Molecule name : EP-2101; IDM2101; OSE-2101;

Codes from synonyms : CDR0000306497;

Details

Origin ID

C26645;

UMLS CUI

C1327951;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- EP-2101/Montanide ISA-51 [NCIt concept]

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Main resources

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