Melanoma-Associated Antigen 2

Preferred Label : Melanoma-Associated Antigen 2;

NCIt synonyms : Melanoma Antigen 2; MAGEA2; MAGE-2 Antigen; CT1.2; Cancer/Testis Antigen 1.2; MAGE-A2;

NCIt definition : Melanoma-associated antigen 2 (314 aa, 35 kDa) is encoded by the human MAGEA2 and MAGEA2B genes. This protein plays a role in the modulation of p53-dependent signaling pathways.;

Détails

Origin ID

C104501;

UMLS CUI

C3539826;

OMIM relation
- Melanoma antigen, family a, 2 [OMIM gene]
- Melanoma antigen, family a, 2b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cancer Gene [NCIt concept]
- MAGEA2 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Testis [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune Response Process [NCIt concept]
- Metastasis Induction [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumorigenesis [NCIt concept]
is_target
- 6 Melanoma Helper Peptide Vaccine [NCIt concept]
- Multi-neo-epitope Vaccine OSE 2101 [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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