Ribonucleoside-Diphosphate Reductase M2

Preferred Label : Ribonucleoside-Diphosphate Reductase M2;

NCIt synonyms : RRM2; Ribonucleotide Reductase M2 Polypeptide; R2; EC 1.17.4.1; Ribonucleotide Reductase, Small Subunit; RR2; RRM2 Protein; Ribonucleotide Reductase Small Chain; Ribonucleotide Reductase, M2 Subunit; Ribonucleotide Reductase, R2 Subunit; Ribonucleoside-Diphosphate Reductase-M2 Chain; Ribonucleoside-Diphosphate Reductase M2 Chain; Ribonucleotide Reductase Small Subunit;

NCIt definition : Ribonucleoside-diphosphate reductase subunit M2 (389 aa, 45 kDa) is encoded by the human RRM2 gene. This protein plays a role in the reduction of ribonucleotides to form deoxyribonucleotides.;

Details

Origin ID

C26621;

UMLS CUI

C1454300;

Currated CISMeF NLP mapping
- ribonucleotide reductase R2 subunit [MeSH concept]
- ribonucleotide reductase R2 subunit [MeSH Supplementary Concept]
OMIM relation
- Ribonucleotide reductase regulatory subunit m2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- RRM2 protein, human [MeSH concept]
- ribonucleotide reductase M2 [MeSH Supplementary Concept]
- ribonucleotide reductase M2 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- RRM2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Ribonucleotide Reductase Subunit Gene [NCIt concept]
gene_product_has_chemical_classification
- Ribonucleotide Reductase Subunit [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- E2F Transcription Factor Pathway [NCIt concept]
- Glutathione Metabolism Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
- p53 Signaling Pathway KEGG [NCIt concept]
gene_product_is_physical_part_of
- Ribonucleotide Reductase [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Replication [NCIt concept]
- DNA Synthesis [NCIt concept]
- Drug Resistance Process [NCIt concept]
- RNA Synthesis [NCIt concept]
is_target
- Antisense Oligonucleotide GTI-2040 [NCIt concept]

Keyword's position in hierarchy(ies) :

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