Epidermal Growth Factor Receptor Kinase Pathway Substrate 8

Preferred Label : Epidermal Growth Factor Receptor Kinase Pathway Substrate 8;

NCIt synonyms : Epidermal Growth Factor Receptor Kinase Substrate EPS8; EPS8; Epidermal Growth Factor Receptor Pathway Substrate 8; EGF Receptor Pathway Substrate-8;

NCIt definition : Epidermal growth factor receptor kinase substrate 8 (822 aa, 92 kDa) is encoded by the human EPS8 gene. This protein is involved in the regulation of both signal transduction and actin cytoskeletal remodeling.;

Details

Origin ID

C26178;

UMLS CUI

C1455518;

Automatic exact mappings (from CISMeF team)
- Epidermal growth factor receptor pathway substrate 8 [OMIM gene]
- epidermal growth factor receptor pathway substrate 8 [ORDO Gene]
- epidermal growth factor receptor pathway substrate 8 [HGNC gene]
OMIM relation
- Epidermal growth factor receptor pathway substrate 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- EPS8 protein, human [MeSH Supplementary Concept]
- EPS8 protein, human [MeSH concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- EPS8 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Amphipathic Alpha Helix [NCIt concept]
- PH Domain [NCIt concept]
- Proline-Rich Domain [NCIt concept]
- SH3 Domain [NCIt concept]
gene_product_is_element_in_pathway
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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