" /> Apolizumab - CISMeF





Preferred Label : Apolizumab;

NCIt synonyms : Monoclonal antibody 1D10; Monoclonal Antibody Hu1D10; MoAb Hu1D10; 1D10 Anti-lymphoma Antibody; MAbHu1D10;

NCIt related terms : MoAb: Hu1D10;

NCIt definition : A humanized monoclonal antibody directed against 1D10, a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic B cells. Apolizumab induces complement-mediated cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and apoptosis of 1D10 antigen-positive B cells in vitro. (NCI04);

Alternative definition : NCI-GLOSS: A substance being studied in the treatment of hematologic (blood) cancers. Apolizumab binds to a protein called ID10, which is found on the surface of some types of immune cells and cancer cells. It may help the immune system kill cancer cells. It is a type of monoclonal antibody.;

UNII : G88KCP51RE;

CAS number : 267227-08-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 267227-08-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Remitogen;

NSC code : 704867; 710066;

Codes from synonyms : CDR0000045051; NSC0710066;

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15/05/2024


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