Rho Guanine Nucleotide Exchange Factor 3

Preferred Label : Rho Guanine Nucleotide Exchange Factor 3;

NCIt synonyms : Exchange Factor Found in Platelets and Leukemic and Neuronal Tissues; ARHGEF3; XPLN;

NCIt definition : Rho guanine nucleotide exchange factor 3 (526 aa, 60 kDa) is encoded by the human ARHGEF3 gene. This protein plays a role in the regulation of guanine nucleotide exchange to regulate GTPase-dependent signaling.;

Details

Origin ID

C217111;

OMIM relation
- Rho guanine nucleotide exchange factor 3 [OMIM gene]
gene_encodes_gene_product
- ARHGEF3 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_structural_domain_or_motif
- DH Domain [NCIt concept]
- PH Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Post-Translational Modification [NCIt concept]
- Signal Transduction [NCIt concept]
- Skeletal Development [NCIt concept]

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