DNA Repair Protein RAD51 Homolog 3

Preferred Label : DNA Repair Protein RAD51 Homolog 3;

NCIt synonyms : RAD51L2; RAD51C; Yeast RAD51 Homolog 3; RAD51-Like Protein 2; RAD51 Homolog C; RAD51 Homolog-C Protein;

NCIt definition : DNA repair protein RAD51 homolog 3 (376 aa, 42 kDa) is encoded by the human RAD51C gene. This protein is involved in the homologous recombination pathway for DNA repair.;

NCIt note : RAD51 family members are strand-transfer proteins thought involved in recombinational repair of damaged DNA and in meiotic recombination. RAD51C protein interacts strongly with RAD51B and moderately with XRCC3 DNA repair proteins, but not with itself. The RAD51C/XRCC3 complex binds single-stranded, but not duplex, DNA. (from Swiss-Prot, OMIM, and NCI);

Details

Origin ID

C21209;

UMLS CUI

C1448265;

OMIM relation
- Rad51 paralog C [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RAD51C protein, human [MeSH Supplementary Concept]
- RAD51C protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- RAD51C Gene [NCIt concept]
gene_product_expressed_in_tissue
- Myocardium [NCIt concept]
- Prostate Gland [NCIt concept]
- Spleen [NCIt concept]
- Testis [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- DNA Binding Protein [NCIt concept]
- Fanconi Anemia Complementation Group Protein [NCIt concept]
- Hydrolase [NCIt concept]
gene_product_is_element_in_pathway
- Homologous Recombination Pathway [NCIt concept]
gene_product_is_physical_part_of
- BCDX2 Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Repair [NCIt concept]
- Meiotic Recombination [NCIt concept]
- Recombination Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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