Low Density Lipoprotein Receptor Adapter Protein 1

Preferred Label : Low Density Lipoprotein Receptor Adapter Protein 1;

NCIt synonyms : Low Density Lipoprotein Receptor Adaptor Protein 1; LDLRAP1; Autosomal Recessive Hypercholesterolemia Protein;

NCIt definition : Low density lipoprotein receptor adapter protein 1 (308 aa, 34 kDa) is encoded by the human LDLRAP1 gene. This protein plays a role in receptor-mediated endocytosis involving LDL receptor.;

Details

Origin ID

C202913;

UMLS CUI

C1172958;

OMIM relation
- Low density lipoprotein receptor adaptor protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- LDLRAP1 protein, human [MeSH Supplementary Concept]
- LDLRAP1 protein, human [MeSH concept]
gene_encodes_gene_product
- LDLRAP1 Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Coated Pit [NCIt concept]
- Cytoplasm [NCIt concept]
- Early Endosome [NCIt concept]
- Membrane of the Endosome [NCIt concept]
gene_product_has_structural_domain_or_motif
- PH Domain [NCIt concept]
- PTB Domain [NCIt concept]
gene_product_is_element_in_pathway
- Endocytosis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cholesterol Homeostasis [NCIt concept]
- Endocytotic Process [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Mediated Endocytosis [NCIt concept]
- Steroid Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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