Ras/Rap GTPase-Activating Protein SynGAP

Preferred Label : Ras/Rap GTPase-Activating Protein SynGAP;

NCIt synonyms : Synaptic Ras-GTPase-Activating Protein 1; Synaptic Ras GTPase Activating Protein 1; Neuronal RasGAP; Synaptic Ras-GAP 1; Ras GTPase-Activating Protein SynGAP; Synaptic Ras GTPase-Activating Protein 1; SYNGAP1;

NCIt definition : Ras/Rap GTPase-activating protein SynGAP (1343 aa, 148 kDa) is encoded by the human SYNGAP1 gene. This protein plays a role in N-methyl-D-aspartate receptor complex activation of Ras/Rap GTPase activity.;

Details

Origin ID

C190811;

UMLS CUI

C1436390;

OMIM relation
- Synaptic ras-gtpase-activating protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SYNGAP1 protein, human [MeSH Supplementary Concept]
- SYNGAP1 protein, human [MeSH concept]
gene_encodes_gene_product
- SYNGAP1 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
- Synapse [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2 Domain [NCIt concept]
- PH Domain [NCIt concept]
- SH3-Binding Motif [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Intracellular Signaling Process [NCIt concept]
- Neural Development [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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