Latent Membrane Protein 1

Preferred Label : Latent Membrane Protein 1;

NCIt synonyms : Protein p63; LMP-1; EBV Latent Membrane Protein 1; EBV LMP1; EBV LMP-1;

NCIt related terms : LMP1; Latent Membrane Protein-1;

NCIt definition : Latent membrane protein 1 (386 aa, 42 kDa) is encoded by the Epstein-Barr virus LMP1 gene. This protein is involved in both the activation of nuclear factor-kappa-B family signaling pathways and the inhibition of apoptosis of infected B-lymphocytes.;

NCIt note : Latent membrane protein 1 functions as a constitutively active tumor necrosis factor receptor and interacts with host tumor necrosis factor receptor-associated factor (TRAF) proteins, including TRAF1, TRAF2, TRAF3 and TRAF5. (UniProt);

Details

Origin ID

C18863;

UMLS CUI

C1334346;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- P63 protein [LOINC component]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- HL Authorized Value Terminology [NCIt concept]
- HL Immunohistochemistry Table [NCIt concept]
gene_encodes_gene_product
- Viral Gene [NCIt concept]
gene_product_has_organism_source
- Virus [NCIt concept]
is_target
- Allogeneic LMP1/LMP2-Specific Cytotoxic T-Lymphocytes [NCIt concept]
- Autologous LMP1-/LMP2- Specific Cytotoxic T-Lymphocytes [NCIt concept]
- DNR-expressing Nasopharyngeal Carcinoma-specific Cytotoxic T-Lymphocytes [NCIt concept]
- LMP1/BARF1/EBNA1-specific Cytotoxic T-lymphocytes [NCIt concept]
- TGF-beta-Resistant LMP-Specific Cytotoxic T-Lymphocytes [NCIt concept]

Keyword's position in hierarchy(ies) :

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