Ras GTPase-Activating Protein nGAP

Preferred Label : Ras GTPase-Activating Protein nGAP;

NCIt synonyms : RAS Protein Activator Like 2; RASAL2; RAS Protein Activator-Like 2;

NCIt definition : Ras GTPase-activating protein nGAP (1139 aa, 129 kDa) is encoded by the human RASAL2 gene. This protein plays a role in Ras GTPase activation and the inhibition of cyclic AMP signaling.;

Details

Origin ID

C185580;

UMLS CUI

C3501226;

Automatic exact mappings (from CISMeF team)
- RAS protein activator like 2 [HGNC gene]
- Ras protein activator-like 2 [OMIM gene]
OMIM relation
- Ras protein activator-like 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RASAL2 protein, human [MeSH Supplementary Concept]
- RASAL2 protein, human [MeSH concept]
gene_encodes_gene_product
- RASAL2 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2 Domain [NCIt concept]
- PH Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Signal Transduction Inhibition [NCIt concept]

Keyword's position in hierarchy(ies) :

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