Protein C-ets-2

Preferred Label : Protein C-ets-2;

NCIt synonyms : ETS2; c-Ets-2; ETS2 Protein;

NCIt definition : Protein C-ets-1 (441 aa, 50 kDa) is encoded by the human ETS1 gene. This protein plays a role in transcriptional regulation that is associated with cell motility, apoptosis induction, cell cycle regulation and immune responses.;

NCIt note : ETS2 Protein activity is potentiated by signaling through the RAS-RAF-MEK kinase cascade and inhibited by direct interaction with the HLH ID1 protein. (OMIM);

Details

Origin ID

C17482;

UMLS CUI

C0107720;

OMIM relation
- Ets protooncogene 2, transcription factor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ETS2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- ETS Family Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- ETS Domain [NCIt concept]
gene_product_is_biomarker_type
- Tumor Marker [NCIt concept]
gene_product_is_element_in_pathway
- Dorso-Ventral Axis Formation Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- Macrophage Differentiation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Skeletal Development [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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