F-Box/LRR-Repeat Protein 4

Preferred Label : F-Box/LRR-Repeat Protein 4;

NCIt synonyms : F-Box and Leucine-Rich Repeat Protein 4; FBXL4; F-Box Protein FBL4/FBL5; F-Box and Leucine Rich Repeat Protein 4;

NCIt definition : F-box/LRR-repeat protein 4 (621 aa, 70 kDa) is encoded by the human FBXL4 gene. This protein is involved in the maintenance of mitochondrial DNA and the regulation of ubiquitin-dependent protein catabolism.;

NCI Metathesaurus CUI : CL577281;

Details

Origin ID

C172119;

UMLS CUI

C5401444;

Automatic exact mappings (from CISMeF team)
- F-box and leucine rich repeat protein 4 [ORDO Gene]
- F-box and leucine rich repeat protein 4 [HGNC gene]
- F-box and leucine-rich repeat protein 4 [OMIM gene]
OMIM relation
- F-box and leucine-rich repeat protein 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- FBXL4 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Intermembrane Space of the Mitochondrion [NCIt concept]
- Nuclear Structure [NCIt concept]
gene_product_has_structural_domain_or_motif
- F-Box Domain [NCIt concept]
- Leucine-Rich Repeat [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein-Protein Interaction [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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