Preferred Label : High-Dose Methotrexate Regimen;

NCIt synonyms : Methotrexate Sodium High-Dose Regimen; High-Dose Methotrexate Sodium Regimen; Methotrexate High-Dose Regimen; High-Dose MTX Regimen;

NCIt definition : A regimen consisting of high-dose methotrexate that may be used in the treatment of chronic lymphocytic leukemia (CLL); small lymphocytic, primary central nervous system (CNS), and diffuse large B-cell lymphomas; bone cancer, and breast cancer leptomeningeal metastases.;

NCI Metathesaurus CUI : CL969028;

Details


Main resources

You can consult :


https://ansm.sante.fr/informations-de-securite/methotrexate-haute-dose-mtx-hd-lansm-rappelle-les-mesures-generales-de-prevention-du-risque-de-nephrotoxicite
2022
false
false
false
France
French
pharmacovigilance note
guidelines for drug use
methotrexate
High-Dose Methotrexate Regimen
methotrexate
antimetabolites, antineoplastic
antimetabolites, antineoplastic
hematologic neoplasms
osteosarcoma
risk
acute kidney injury
renal insufficiency, acute
Methotrexate overdose (disorder)
kidney function tests
adult
aged
risk management
drug interactions
continuity of patient care
methotrexate
methotrexate
methotrexate
poisoning
poisoning
leucovorin
glucarpidase

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07/05/2025


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