Cancer/Testis Antigen 2 Isoform LAGE-1A

Preferred Label : Cancer/Testis Antigen 2 Isoform LAGE-1A;

NCIt synonyms : LAGE-1a Protein; Cancer/Testis Antigen 6.2a; Isoform LAGE-1A; CT6.2a; LAGE-1S; LAGE-1A; L Antigen Family Member 1 Isoform A;

NCIt definition : Cancer/testis antigen 2 (180 aa, 18 kDa) is encoded by the human CTAG2 gene. This protein may play a role in tumorigenesis of several tissues.;

NCIt note : UniProt has designated isoform LAGE-1B as the canonical form of this protein; thus, isoform LAGE-1A is the alternative isoform produced by alternative splicing of the CTAG2 gene.;

NCI Metathesaurus CUI : CL554383;

Details

Origin ID

C153125;

UMLS CUI

C4722882;

Automatic exact mappings (from CISMeF team)
- Cancer/testis antigen 2 [OMIM gene]
- cancer/testis antigen 2 [HGNC gene]
OMIM relation
- Cancer/testis antigen 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CTAG2 Gene [NCIt concept]
- Cancer Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Metastasis Induction [NCIt concept]
- Tumorigenesis [NCIt concept]
is_target
- Anti-NY-ESO1/LAGE-1A TCR/scFv Anti-CD3 IMCnyeso [NCIt concept]
- Trastuzumab Imbotolimod [NCIt concept]

Keyword's position in hierarchy(ies) :

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