Pleckstrin Homology Domain-Containing Family G Member 5

Preferred Label : Pleckstrin Homology Domain-Containing Family G Member 5;

NCIt synonyms : Guanine Nucleotide Exchange Factor 720; GEF720; PH Domain-Containing Family G Member 5; Pleckstrin Homology Domain-Containing Protein, Family G. Member 5; PLEKHG5; Synectin-Binding Guanine Exchange Factor; Pleckstrin Homology Domain- and RhoGEF Domain-Containing Protein G5;

NCIt definition : Pleckstrin homology domain-containing family G member 5 (1062 aa, 117 kDa) is encoded by the human PLEKHG5 gene. This protein plays a role in the activation of transforming protein RhoA and nuclear factor kappa B signaling pathways.;

Details

Origin ID

C150303;

UMLS CUI

C2001300;

Automatic exact mappings (from CISMeF team)
- Pleckstrin homology domain- and rhogef domain-containing protein g5 [OMIM gene]
- pleckstrin homology and RhoGEF domain containing G5 [ORDO Gene]
- pleckstrin homology and RhoGEF domain containing G5 [HGNC gene]
OMIM relation
- Pleckstrin homology domain- and rhogef domain-containing protein g5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PLEKHG5 protein, human [MeSH concept]
- PLEKHG5 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- PLEKHG5 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_expressed_in_tissue
- Peripheral Nervous System [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- DH Domain [NCIt concept]
- PH Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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