Immunoglobulin Hypervariable Region

Preferred Label : Immunoglobulin Hypervariable Region;

NCIt synonyms : Hypervariable Loop; Complementarity-Determining Region; CDR; Complementarity Determining Region;

NCIt definition : Within the variable domain of an antibody molecule are three regions called hypervariable regions, areas of high sequence diversity. These regions form the surfaces that are responsible for antigen binding interactions. Also known as complementarity determining region or hypervariable loop.;

Details

Origin ID

C13342;

UMLS CUI

C0021024;

Anatomic structure is physical part of
- Immunoglobulin Variable Region [NCIt concept]
Automatic exact mappings (from CISMeF team)
- 2'-deoxycytidine [Substance BNPC]
- Aldo-keto reductase family 1, member c4 [OMIM gene]
- Cerebellar degeneration-related autoantigen 1 [OMIM gene]
- Chlordecone reductase (substance) [SNOMED CT concept]
- Coding region [OMIConto structure]
- RUNX1 partner transcriptional co-repressor 1 [ORDO Gene]
- aldo-keto reductase family 1 member C4 [ORDO Gene]
- deoxycytidine [MeSH Descriptor]
- deoxycytidine [MeSH concept]
- rotator cuff [MeSH Descriptor]
Currated CISMeF NLP mapping
- Immunoglobulin, hypervariable region (substance) [SNOMED CT concept]
- antibody hypervariable region [SNOMED Notion]
- complementarity determining regions [MeSH Descriptor]
- complementarity determining regions [MeSH concept]
- immunoglobulin, hypervariable region [SNOMED Notion]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Immunoglobulin, hypervariable region (substance) [SNOMED CT concept]
- antibody hypervariable region [SNOMED Notion]
- complementarity determining regions [MeSH concept]
- complementarity determining regions [MeSH Descriptor]
- immunoglobulin, hypervariable region [SNOMED Notion]
is_structural_domain_or_motif_of_gene_product
- Immunoglobulin Heavy Chain [NCIt concept]
- Immunoglobulin Light Chain [NCIt concept]
- Immunoglobulin Light Chain, Kappa [NCIt concept]
- Immunoglobulin Light Chain, Lambda [NCIt concept]
- T-Cell Receptor Alpha Chain [NCIt concept]
- T-Cell Receptor Beta Chain [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients